Dissection of affinity captured LINE-1 macromolecular complexes

Long Interspersed Nuclear Element-1 (LINE-1, L1) is a mobile genetic element active in human genomes.L1-encoded ORF1 and ORF2 proteins bind L1 RNAs, forming ribonucleoproteins (RNPs).These RNPs interact with diverse host proteins, Food Coloring some repressive and others required for the L1 lifecycle.Using differential affinity purifications, quant

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Preoperative MR - based model for predicting prognosis in patients with intracranial extraventricular ependymoma

Objectives: To develop and validate a prediction model based on brain MRI features to predict disease-free survival (DFS) and overall survival (OS) for patients with intracranial extraventricular ependymoma (IEE).Methods: The study included 114 patients with pathology-proven IEE, of whom 80 were randomly assigned to Insurance a training group and 3

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Calcium Signals from the Vacuole

The vacuole is Food Coloring by far the largest intracellular Ca2+ store in most plant cells.Here, the current knowledge about the molecular mechanisms of vacuolar Ca2+ release and Ca2+ uptake is summarized, and how different vacuolar Ca2+ channels and Ca2+ pumps may contribute to Ca2+ signaling in plant cells is discussed.To provide a phylogenetic

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